{
  "types": [
    "MolecularSequence"
  ],
  "MolecularSequence": {
    "elements": {
      "MolecularSequence.type": {
        "binding-valueset-changed": true,
        "binding-status": "changed",
        "old-binding": {
          "reference": "http://hl7.org/fhir/ValueSet/sequence-type|4.0.0",
          "strength": "required"
        },
        "new-binding": {
          "reference": "http://hl7.org/fhir/ValueSet/sequence-type|4.3.0",
          "strength": "required"
        }
      },
      "MolecularSequence.referenceSeq.orientation": {
        "binding-valueset-changed": true,
        "binding-status": "changed",
        "old-binding": {
          "reference": "http://hl7.org/fhir/ValueSet/orientation-type|4.0.0",
          "strength": "required"
        },
        "new-binding": {
          "reference": "http://hl7.org/fhir/ValueSet/orientation-type|4.3.0",
          "strength": "required"
        }
      },
      "MolecularSequence.referenceSeq.strand": {
        "binding-valueset-changed": true,
        "binding-status": "changed",
        "old-binding": {
          "reference": "http://hl7.org/fhir/ValueSet/strand-type|4.0.0",
          "strength": "required"
        },
        "new-binding": {
          "reference": "http://hl7.org/fhir/ValueSet/strand-type|4.3.0",
          "strength": "required"
        }
      },
      "MolecularSequence.quality.type": {
        "binding-valueset-changed": true,
        "binding-status": "changed",
        "old-binding": {
          "reference": "http://hl7.org/fhir/ValueSet/quality-type|4.0.0",
          "strength": "required"
        },
        "new-binding": {
          "reference": "http://hl7.org/fhir/ValueSet/quality-type|4.3.0",
          "strength": "required"
        }
      },
      "MolecularSequence.repository.type": {
        "binding-valueset-changed": true,
        "binding-status": "changed",
        "old-binding": {
          "reference": "http://hl7.org/fhir/ValueSet/repository-type|4.0.0",
          "strength": "required"
        },
        "new-binding": {
          "reference": "http://hl7.org/fhir/ValueSet/repository-type|4.3.0",
          "strength": "required"
        }
      },
      "MolecularSequence.structureVariant.variantType": {
        "binding-valueset-changed": true,
        "binding-status": "changed",
        "old-binding": {
          "reference": "http://loinc.org/vs/LL379-9|4.0.0",
          "strength": "required"
        },
        "new-binding": {
          "reference": "http://loinc.org/vs/LL379-9|4.3.0",
          "strength": "required"
        }
      }
    },
    "status": "changed"
  }
}